Hematology: Basic Principles and Practice

Extensively revised, comprehensive  content from leading global contributors ensures that Hematology, 8th  Edition, remains your #1 choice for expert guidance in all areas of this  rapidly advancing subspecialty. This edition reflects the numerous  advances that are redefining the field and dramatically influencing new  approaches to diagnosis, treatment, and outcomes. Well-illustrated and  clinically focused, it details the basic science and clinical practice  of hematology and hematopoietic cellular therapy―covering virtually all  aspects of hematology in one definitive resource.

• Covers  all hematologic disorders, including comprehensive discussions of  hematologic malignancies, individualized patient care, cell-based  therapies, transplantation, transfusion medicine, hemostasis,  thrombosis, and consultative hematology―in one convenient volume. 
• Provides state-of-the-art guidance from global experts at the forefront of the latest research and clinical practice. 
• Provides  extensive updates throughout on basic science research, advances in  molecular diagnostics, new drugs, immunotherapies, personalized  medicine, laboratory medicine, transfusion medicine, stem cell  transplantation, and clinical treatment for all hematologic malignancies  and non-malignancies 
• Contains  new chapters on gene editing; the impact of mitochondria on  hematopoiesis; myelodysplastic syndrome/myeloproliferative neoplasm  overlap syndromes; immunotherapy and management of its toxicities;  transfusion medicine in sickle cell disease; principles of radiation  therapy; and COVID-19, including complications of vaccination and its  impact on the hematologic system. 
• Discusses  many new advances in the field, including details and the future of  gene therapy for hemophilia, gene editing for sickle cell disease and  thalassemia, the evolution of cellular therapy, use of cells,  transfusion medicine vs. protein therapy, gene sequencing,  immunotherapy, and new targeted drugs. 
• Includes  more decision-making algorithms for formulating diagnoses and  personalized treatment plans for those highly complex disorders that  require individualized approaches. 
• Addresses the effects of aging on hematopoiesis and on the manifestations of a variety of hematologic disorders. 
• Discusses cardio-oncology and its impact on the treatment of patients with hematologic disorders. 
• Presents relevant basic science as background for clinical application in later sections.